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pentobarbital will raise the degree or influence of ivosidenib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Coadministration of ivosidenib with sturdy CYP3A4 inducers lessened ivosidenib plasma concentrations.pentobarbital will decrease the extent or result of abemaciclib by affecting hepatic/intestinal enz

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